Article
Testing Psychosis Phenotypes From Bipolar-Schizophrenia Network for Intermediate Phenotypes for Clinical Application: Biotype Characteristics and Targets.
Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Aug 2020
Clementz Brett A, Trotti Rebekah L, Pearlson Godfrey D, Keshavan Matcheri S, Gershon Elliot S, Keedy Sarah K, Ivleva Elena I, McDowell Jennifer E, Tamminga Carol A
Abstract excerpt
BACKGROUND: Psychiatry aspires to the molecular understanding of its disorders and, with that knowledge, to precision medicine. Research supporting such goals in the dimension of psychosis has been compromised, in part, by using phenomenology alone to estimate disease entities. To this end, we are proponents of a deep phenotyping approach in psychosis, using computational strategies to discover the most...
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