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Article

Shear dependent red blood cell adhesion in microscale flow.

Integrative biology : quantitative biosciences from nano to macro - 23 Apr 2018

Kucukal Erdem, Little Jane A, Gurkan Umut A

Abstract excerpt

Non-adherence and deformability are the key intrinsic biomechanical features of the red blood cell (RBC), which allow it to tightly squeeze and pass through even the narrowest of microcirculatory networks. Blockage of microcirculatory flow, also known as vaso-occlusion, is a consequence of abnormal cellular adhesion to the vascular endothelium. In sickle cell disease (SCD), an inherited anaemia, even though RBCs...

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Share to Anemia, Sickle Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

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Source

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Identifiers

PMID: 29557482
DOI: 10.1039/C8IB00004B
PMCID: PMC6421573

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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