Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy.

doi:10.1161/CIRCGEN.117.001893

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Article

Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy.

Circulation. Genomic and precision medicine - 1 Mar 2018

El-Battrawy Ibrahim, Zhao Zhihan, Lan Huan, Li Xin, Yücel Gökhan, Lang Siegfried, Sattler Katherine, Schünemann Jan-Dierk, Zimmermann Wolfram-Hubertus, Cyganek Lukas, Utikal Jochen, Wieland Thomas, Bieback Karen, Bauer Ralf, Ratte Antonius, Pribe-Wolferts Regina, Rapti Kleopatra, Nowak Daniel, Wittig Janina, Thomas Dierk, Most Patrick, Katus Hugo A, Ravens Ursula, Schmidt Constanze, Borggrefe Martin, Zhou Xiao-Bo, Müller Oliver J, Akin Ibrahim

Abstract excerpt

BACKGROUND: Limb-Girdle muscular dystrophies (LGMD) are a heritable group of genetically determined disorders with a primary involvement of the pelvic or shoulder girdle musculature with partially cardiac manifestation, such as dilated cardiomyopathy (DCM) and life-threatening tachyarrhythmia. We report here that human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes from a patient with LGMD2I and DCM...

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PMID: 29545480
DOI: 10.1161/CIRCGEN.117.001893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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