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Article

Association between XPF polymorphisms and cancer risk: a meta-analysis.

PloS one - 1 Jan 2012

Shi Ting-Yan, He Jing, Qiu Li-Xin, Zhu Mei-Ling, Wang Meng-Yun, Zhou Xiao-Yan, Han Jiali, Yu Hongpin, Zang Rong-Yu, Wei Qingyi

Abstract excerpt

BACKGROUND: Xeroderma pigmentosum complementation group F (XPF or ERCC4) plays a key role in DNA repair that protects against genetic instability and carcinogenesis. A series of epidemiological studies have examined associations between XPF polymorphisms and cancer risk, but the findings remain inconclusive. METHODOLOGY/PRINCIPAL FINDINGS: In this meta-analysis of 47,639 cancer cases and 51,915 controls, by...

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Identifiers

PMID: 22768293
DOI: 10.1371/journal.pone.0038606
PMCID: PMC3388076

Genes

ERCC4

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