Article
Assessing the causal association between 25-hydroxyvitamin D and the risk of oral and oropharyngeal cancer using Mendelian randomization.
International journal of cancer - 1 Sept 2018
Dudding Tom, Johansson Mattias, Thomas Steven J, Brennan Paul, Martin Richard M, Timpson Nicholas J
Abstract excerpt
Circulating 25-hydroxyvitamin D (25OHD) is an appealing potential intervention for cancer risk and has been associated with oral and oropharyngeal cancer risk but evidence is inconsistent. The availability of genetic variants, uncorrelated with known confounders, but predictive of 25OHD and genetic data in a large oral and oropharyngeal cancer collaboration aids causal inference when assessing this association. A...
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