Article
Effects of three permeases on arginine utilization in Saccharomyces cerevisiae.
Scientific reports - 11 Feb 2016
Zhang Peng, Du Guocheng, Zou Huijun, Chen Jian, Xie Guangfa, Shi Zhongping, Zhou Jingwen
Abstract excerpt
Arginine plays an important role in cellular function and metabolism. Arginine uptake mainly occurs through three amino acid permeases, Alp1p, Gap1p and Can1p, which act as both transporters and receptors for amino acid utilization. In this study, seven mutants were constructed with different combinations of permease deficiencies that inhibit arginine utilization. Their effects on arginine metabolism were...
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