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Article

Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10).

Scientific reports - 13 Mar 2018

Sharlin David S, Ng Lily, Verrey François, Visser Theo J, Liu Ye, Olszewski Rafal T, Hoa Michael, Heuer Heike, Forrest Douglas

Abstract excerpt

Transmembrane proteins that mediate the cellular uptake or efflux of thyroid hormone potentially provide a key level of control over neurodevelopment. In humans, defects in one such protein, solute carrier SLC16A2 (MCT8) are associated with psychomotor retardation. Other proteins that transport the active form of thyroid hormone triiodothyronine (T3) or its precursor thyroxine (T4) have been identified in vitro...

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Identifiers

PMID: 29535325
DOI: 10.1038/s41598-018-22553-w
PMCID: PMC5849681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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