Article
Mechanisms of Tissue Injury in Lupus Nephritis.
Trends in molecular medicine - 1 Apr 2018
Flores-Mendoza Giovanna, Sansón Stephanie P, Rodríguez-Castro Santiago, Crispín José C, Rosetti Florencia
Abstract excerpt
Disease heterogeneity remains a major challenge for the understanding of systemic lupus erythematosus (SLE). Recent work has revealed the important role of nonimmune factors in the development of end-organ damage involvement, shifting the current paradigm that views SLE as a disease inflicted by a disturbed immune system on passive target organs. Here, we discuss the pathogenesis of lupus nephritis in a...
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