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Article

[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant  Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Feb 2018

Li Hui, Wang Ying, Yang Jiali, Liu Xiaoming, Shi Juan

Abstract excerpt

BACKGROUND: The incidence of lung cancer is gradually increased, and the cystic fibrosis transmembrane conductance regulator (CFTR) has recently demonstrated to have an implication in the deoncogenesis and malignant transformation of many types of cancers. The aim of this study is to investigate impacts of CFTR on the malignant features of lung adenocarcinoma A549 cells. METHODS: The capacity of cell...

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Source

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Identifiers

PMID: 29526175
DOI: 10.3779/j.issn.1009-3419.2018.02.03
PMCID: PMC5973018

Genes

CFTR
KRAS
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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