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CAAT/enhancer binding protein-homologous protein deficiency attenuates liver ischemia/reperfusion injury in mice.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 May 2018

Wada Seidai, Hatano Etsuro, Yoh Tomoaki, Nakamura Naohiko, Okuda Yukihiro, Okuno Masayuki, Kasai Yosuke, Iwaisako Keiko, Seo Satoru, Taura Kojiro, Uemoto Shinji

Abstract excerpt

Ischemia/reperfusion injury (IRI) is one of the main causes of liver dysfunction after liver surgery. Involvement of endoplasmic reticulum (ER) stress in various diseases has been demonstrated, and CAAT/enhancer binding protein-homologous protein (CHOP) is a transcriptional regulator that is induced by ER stress. It is also a key regulator of ER stress-mediated apoptosis. The aim of this study was to investigate...

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PMID: 29524333
DOI: 10.1002/lt.25053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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