Article
The role of atorvastatin in suppressing tumor growth of uterine fibroids.
Journal of translational medicine - 9 Mar 2018
Shen Zhaojun, Li Saisai, Sheng Bo, Shen Qi, Sun Lu-Zhe, Zhu Haiyan, Zhu Xueqiong
Abstract excerpt
BACKGROUND: Medical therapeutic options remain quite limited for uterine fibroids treatment. Statins, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, have anti-tumoral effects on multiple cancer types, however, little is known about their effects on uterine fibroids. METHODS: Initially, we conducted a retrospective study of 120 patients with uterine fibroids and hyperlipidemia from the...
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