Article

Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis

2020-12-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene (e.g. PTEN ) or microRNAs (e.g. miR-23a and miR-29b). Metapristone is a hormone-related drug, which is widely used in clinical treatment of endometrial can...

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Literature Corpus work: 70b184aa-4a9d-54e8-ab84-2d7fae5b2a9e
DOI: 10.21203/rs.2.23357/v5

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