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Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas

9 Mar 2018

Abstract excerpt

BACKGROUND: We have previously identified tissue inhibitor of metalloproteinases-1 (TIMP-1) as a prognostic marker in glioblastomas. TIMP-1 has been associated with chemotherapy resistance, and CD63, a known TIMP-1-binding protein, has been suggested to be responsible for this effect. The aim of this study was to assess CD63 expression in astrocytomas focusing on the prognostic potential of CD63 alone and in...

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PMID: 29523123
DOI: 10.1186/s12885-018-4179-y

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