Article
Control of hmu Heme Uptake Genes in Yersinia pseudotuberculosis in Response to Iron Sources.
Frontiers in cellular and infection microbiology - 1 Jan 2018
Schwiesow Leah, Mettert Erin, Wei Yahan, Miller Halie K, Herrera Natalia G, Balderas David, Kiley Patricia J, Auerbuch Victoria
Abstract excerpt
Despite the mammalian host actively sequestering iron to limit pathogenicity, heme (or hemin when oxidized) and hemoproteins serve as important sources of iron for many bloodborne pathogens. The HmuRSTUV hemin uptake system allows Yersinia species to uptake and utilize hemin and hemoproteins as iron sources. HmuR is a TonB-dependent outer membrane receptor for hemin and hemoproteins. HmuTUV comprise a inner...
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