Article
Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization.
Infection and immunity - 1 Aug 1999
Thompson J M, Jones H A, Perry R D
Abstract excerpt
Sequence analysis of the hemin uptake locus (hmu) of Yersinia pestis revealed five genes, hmuRSTUV, required for use of hemin and hemoproteins as iron sources. The translated gene products have homologies with proteins of the hemin transport genes of several gram-negative bacteria. Promoters were identified upstream of hmuP'R (p1) and upstream of hmuS (p2); p1, which contains a Fur box, is regulated by iron and...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Female
- Genes, Bacterial
- Hemeproteins
- Hemin
- Hemoglobins
- Iron
- Mice
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Rabbits
- Yersinia pestis