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Article

IGF Binding Protein-5 Induces Cell Senescence

19 Feb 2018

Abstract excerpt

Cellular senescence is the complex process of deterioration that drives the aging of an organism, resulting in the progressive loss of organ function and eventually phenotypic aging. Senescent cells undergo irreversible growth arrest, usually by inducing telomere shortening. Alternatively, senescence may also occur prematurely in response to various stress stimuli, such as oxidative stress, DNA damage, or...

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PMID: 29515523
DOI: 10.3389/fendo.2018.00053

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