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Article

IL-6-STAT3 signaling and premature senescence

23 Aug 2013

Abstract excerpt

Cytokines play several roles in developing and/or reinforcing premature cellular senescence of young cells. One such cytokine, interleukin-6 (IL-6), regulates senescence in some systems in addition to its known functions of immune regulation and promotion of tumorigenesis. In this review, we describe recent advances in studies on the roles of IL-6 and its downstream signal transducer and activator of...

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PMID: 24416650
DOI: 10.4161/jkst.25763

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