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Gut microbial RNA and DNA analysis predicts hospitalizations in cirrhosis

7 Mar 2018

Abstract excerpt

BACKGROUND: Cirrhosis is associated with gut microbial changes, but current 16S rDNA techniques sequence both dead and live bacteria. We aimed to determine the rRNA content compared with DNA from the same stool sample to evaluate cirrhosis progression and predict hospitalizations. METHODS: Cirrhotics and controls provided stool for RNA and DNA analysis. Comparisons were made between cirrhotics/controls and within...

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PMID: 29515036
DOI: 10.1172/jci.insight.98019

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