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A gut bacterial signature in blood and liver tissue characterizes cirrhosis and hepatocellular carcinoma

14 Jun 2023

Abstract excerpt

BACKGROUND: HCC is the leading cause of cancer in chronic liver disease. A growing body of experimental mouse models supports the notion that gut-resident and liver-resident microbes control hepatic immune responses and, thereby, crucially contribute to liver tumorigenesis. However, a comprehensive characterization of the intestinal microbiome in fueling the transition from chronic liver disease to HCC in humans...

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PMID: 37314752
DOI: 10.1097/hc9.0000000000000182

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