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A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments

1 Nov 2023

Abstract excerpt

Background: This study aims to investigate the association between immune cells and the development of COPD, while providing a new method for the diagnosis of COPD according to the changes in immune microenvironment. Methods: In this study, the "CIBERSORT" algorithm was used to estimate the tissue infiltration of 22 types of immune cells in GSE20257 and GSE10006. The "limma" package was used for differentially...

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PMID: 38050560
DOI: 10.2147/jir.s438308

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