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Article

Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy.

Cell reports - 6 Mar 2018

Walls Stanley M, Cammarato Anthony, Chatfield Dale A, Ocorr Karen, Harris Greg L, Bodmer Rolf

Abstract excerpt

Lipotoxic cardiomyopathy (LCM) is characterized by abnormal myocardial accumulation of lipids, including ceramide; however, the contribution of ceramide to the etiology of LCM is unclear. Here, we investigated the association of ceramide metabolism and ceramide-interacting proteins (CIPs) in LCM in the Drosophila heart model. We find that ceramide feeding or ceramide-elevating genetic manipulations are strongly...

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Identifiers

PMID: 29514098
DOI: 10.1016/j.celrep.2018.02.034
PMCID: PMC6242704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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