Article
Interaction between alcohol consumption and methylenetetrahydrofolate reductase polymorphisms in thyroid cancer risk: National Cancer Center cohort in Korea.
Scientific reports - 6 Mar 2018
Yang Sarah, Lee Jeonghee, Park Yoon, Lee Eun Kyung, Hwangbo Yul, Ryu Junsun, Sung Joohon, Kim Jeongseon
Abstract excerpt
The effect of alcohol intake on thyroid cancer is unestablished, and its interaction effects with genetic susceptibility are unclear. In this case-control study, the relationship among alcohol intake, the methylenetetrahydrofolate reductase (MTHFR) gene, and thyroid cancer risk has been evaluated. In total, 642 cases and 642 controls of Korean origin were included, and the genetic variants C677T and A1298C of the...
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