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Article

Loss of Actin-Based Motility Impairs Ectromelia Virus Release In Vitro but Is Not Critical to Spread In Vivo.

Viruses - 5 Mar 2018

Duncan Melanie Laura, Horsington Jacquelyn, Eldi Preethi, Al Rumaih Zahrah, Karupiah Gunasegaran, Newsome Timothy P

Abstract excerpt

Ectromelia virus (ECTV) is an orthopoxvirus and the causative agent of mousepox. Like other poxviruses such as variola virus (agent of smallpox), monkeypox virus and vaccinia virus (the live vaccine for smallpox), ECTV promotes actin-nucleation at the surface of infected cells during virus release. Homologs of the viral protein A36 mediate this function through phosphorylation of one or two tyrosine residues that...

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Identifiers

PMID: 29510577
DOI: 10.3390/v10030111
PMCID: PMC5869504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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