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Article

Packaging of actin into Ebola virus VLPs

1 Dec 2005

Abstract excerpt

The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses. In this report, we sought to determine whether actin is incorporated into Ebola VLPs, and thus may play a role in assembly and/or budding of Ebola virus. Our results indicated that actin and Ebola virus VP40 strongly co-localized in transfected...

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PMID: 16367999
DOI: 10.1186/1743-422x-2-92

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