Article
Inferring Fitness Effects from Time-Resolved Sequence Data with a Delay-Deterministic Model.
Genetics - 1 May 2018
Nené Nuno R, Dunham Alistair S, Illingworth Christopher J R
Abstract excerpt
A common challenge arising from the observation of an evolutionary system over time is to infer the magnitude of selection acting upon a specific genetic variant, or variants, within the population. The inference of selection may be confounded by the effects of genetic drift in a system, leading to the development of inference procedures to account for these effects. However, recent work has suggested that...
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