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Article

Wanted: A population genetic theory of biological noise regulation.

PLoS genetics - 1 Mar 2026

Weinreich Daniel M, Sgouros Tom, Raynes Yevgeniy, Burtsev Hlib, Chang Edison, Rajakumar Sanyu, Bravo Ignacio G, Petak Csenge

Abstract excerpt

Classical population genetics provides a robust, quantitative framework for modeling how natural selection acts on alleles that influence phenotypes with invariant fitness consequences for their carriers, such as running speed or drug resistance. By contrast, modifier theory considers the evolution of alleles that influence population genetic parameter values in their carriers, such as mutation or recombination...

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Identifiers

PMID: 41824490
DOI: 10.1371/journal.pgen.1012066
PMCID: PMC13002102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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