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Article

Wanted: A population genetic theory of biological noise regulation.

PLoS genetics - 1 Mar 2026

Weinreich Daniel M, Sgouros Tom, Raynes Yevgeniy, Burtsev Hlib, Chang Edison, Rajakumar Sanyu, Bravo Ignacio G, Petak Csenge

Abstract excerpt

Classical population genetics provides a robust, quantitative framework for modeling how natural selection acts on alleles that influence phenotypes with invariant fitness consequences for their carriers, such as running speed or drug resistance. By contrast, modifier theory considers the evoluti...

Topics

Selection, Genetic
Genetics, Population
Models, Genetic
Alleles
Phenotype
Animals
Genetic Fitness
Mutation
Evolution, Molecular
Stochastic Processes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41824490
DOI: 10.1371/journal.pgen.1012066
PMCID: PMC13002102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-41824490-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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