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Article

Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion.

The Journal of biological chemistry - 20 Apr 2018

Mitok Kelly A, Freiberger Elyse C, Schueler Kathryn L, Rabaglia Mary E, Stapleton Donald S, Kwiecien Nicholas W, Malec Paige A, Hebert Alexander S, Broman Aimee T, Kennedy Robert T, Keller Mark P, Coon Joshua J, Attie Alan D

Abstract excerpt

The mouse is a critical model in diabetes research, but most research in mice has been limited to a small number of mouse strains and limited genetic variation. Using the eight founder strains and both sexes of the Collaborative Cross (C57BL/6J (B6), A/J, 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HILtJ (NZO), PWK/PhJ (PWK), WSB/EiJ (WSB), and CAST/EiJ (CAST)), we investigated the genetic dependence of...

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Share to Islets of Langerhans
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29496998
DOI: 10.1074/jbc.RA117.001102
PMCID: PMC5912463

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CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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