Article
Human catalase gene promoter haplotype and cardiometabolic improvement after bariatric surgery.
Gene - 20 May 2018
Alili Rohia, Nivet-Antoine Valérie, Saldmann Antonin, Golmard Jean-Louis, Cottart Charles-Henry, Laguillier Christelle, Giral Philippe, Beaudeux Jean-Louis, Bouillot Jean-Luc, Poitou Christine, Clément Karine, Hébert-Schuster Marylise
Abstract excerpt
Although its powerful impact on most co-morbidities has been widely demonstrated, the metabolic outcomes of bariatric surgery (BS) show a great heterogeneity among patients. Haplotypes of one of the major antioxidant enzyme, catalase (CAT), are associated with hypertension, dyslipidemia, and diabetes. The haplotype referred to as CAT1 includes homozygous carriers of CATH1 [-844G,-89A,-20T], whereas CAT2 haplotype...
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