Article
Effects of rs769217 and rs1001179 polymorphisms of catalase gene on blood catalase, carbohydrate and lipid biomarkers in diabetes mellitus.
Free radical research - 1 Oct 2012
Góth László, Nagy Teréz, Kósa Zsuzsanna, Fejes Zsolt, Bhattoa Harjit Pal, Paragh György, Káplár Miklós
Abstract excerpt
Oxidative stress and deficiency of the enzyme catalase, which is the primary scavenger of the oxidant H(2)O(2), may contribute to diabetes. The current study examined two polymorphisms in the catalase gene, -262C>nT in the promoter and 111C>T in exon 9, and their effects on blood catalase activity as well as on concentrations of blood glucose, haemoglobin A1c, triglyceride, cholesterol, HDL, LDL, ApoA-I and ApoB....
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