Novel GREM1 Variations in Sub-Saharan African Patients With Cleft Lip and/or Cleft Palate.

doi:10.1177/1055665618754948

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Article

Novel GREM1 Variations in Sub-Saharan African Patients With Cleft Lip and/or Cleft Palate.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 May 2018

Gowans Lord Jephthah Joojo, Oseni Ganiyu, Mossey Peter A, Adeyemo Wasiu Lanre, Eshete Mekonen A, Busch Tamara D, Donkor Peter, Obiri-Yeboah Solomon, Plange-Rhule Gyikua, Oti Alexander A, Owais Arwa, Olaitan Peter B, Aregbesola Babatunde S, Oginni Fadekemi O, Bello Seidu A, Audu Rosemary, Onwuamah Chika, Agbenorku Pius, Ogunlewe Mobolanle O, Abdur-Rahman Lukman O, Marazita Mary L, Adeyemo A A, Murray Jeffrey C, Butali Azeez

Abstract excerpt

OBJECTIVE: Cleft lip and/or cleft palate (CL/P) are congenital anomalies of the face and have multifactorial etiology, with both environmental and genetic risk factors playing crucial roles. Though at least 40 loci have attained genomewide significant association with nonsyndromic CL/P, these loci largely reside in noncoding regions of the human genome, and subsequent resequencing studies of neighboring candidate...

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PMID: 29489415
DOI: 10.1177/1055665618754948
PMCID: PMC6081638

Genes

GREM1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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