Article

Accumulation of Rare Coding Variants in Genes Implicated in Risk of Human Cleft Lip with or without Cleft Palate

2019-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Cleft lip with/without cleft palate (CLP) is a common craniofacial malformation with complex etiologies, reflecting both genetic and environmental factors. Most of the suspected genetic risk for CLP has yet to be identified. To further classify risk loci and estimate the contribution of rare variants, we sequenced the exons in 49 candidate genes in 323 CLP cases and 211 non-malformed controls. O...

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Literature Corpus work: 6e1edd35-e48b-540c-a9af-bfa0e7fa7e14
DOI: 10.1101/533208

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