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Article

Role of Autophagy in Parkinson's Disease.

Current medicinal chemistry - 1 Jan 2019

Cerri Silvia, Blandini Fabio

Abstract excerpt

Autophagy is an essential catabolic mechanism that delivers misfolded proteins and damaged organelles to the lysosome for degradation. Autophagy pathways include macroautophagy, chaperone-mediated autophagy and microautophagy, each involving different mechanisms of substrate delivery to lysosome. Defects of these pathways and the resulting accumulation of protein aggregates represent a common pathobiological...

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PMID: 29484979
DOI: 10.2174/0929867325666180226094351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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