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Article

Dysregulation of autophagy and mitochondrial function in Parkinson’s disease

31 Oct 2016

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative disease. Increasing evidence supports that dysregulation of autophagy and mitochondrial function are closely related with PD pathogenesis. In this review, we briefly summarized autophagy pathway, which consists of macroautophagy, microautophagy and chaperone-mediated autophagy (CMA). Then, we discussed the involvement of mitochondrial...

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PMID: 27822367
DOI: 10.1186/s40035-016-0065-1

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