Article
High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR.
Helicobacter - 1 Apr 2018
Talarico Sarah, Korson Andrew S, Leverich Christina K, Park Stephanie, Jalikis Florencia G, Upton Melissa P, Broussard Elizabeth, Salama Nina R
Abstract excerpt
BACKGROUND: Treatment of Helicobacter pylori infection is often empiric; however, current guidelines for management of Helicobacter pylori infection advise against the use of standard triple therapy (clarithromycin, amoxicillin, and proton-pump inhibitor) when clarithromycin resistance exceeds 20%. We developed and tested a new culture-free assay to detect clarithromycin resistance-conferring mutations to...
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