Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Droplet Digital PCR-Based Detection of Clarithromycin Resistance in Helicobacter pylori Isolates Reveals Frequent Heteroresistance.

Journal of clinical microbiology - 1 Sept 2018

Sun Lu, Talarico Sarah, Yao Lena, He Lihua, Self Steve, You Yuanhai, Zhang Huifang, Zhang Yiyao, Guo Yongjun, Liu Guodong, Salama Nina R, Zhang Jianzhong

Abstract excerpt

Chronic infection with Helicobacter pylori causes peptic ulcers and stomach cancer in a subset of infected individuals. While standard eradication therapy includes multiple antibiotics, treatment failure due to resistance is an increasing clinical problem. Accurate assessment of H. pylori antimicrobial resistance has been limited by slow growth and sampling of few isolates per subject. We established a method to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clarithromycin
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Mucosa

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Microbial Sensitivity Tests

Share to RNA, Ribosomal, 23S

Source

Open in PubMed Open full text

Identifiers

PMID: 29925646
DOI: 10.1128/JCM.00019-18
PMCID: PMC6113488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Droplet Digital PCR-Based Detection of Clarithromycin Resistance in Helicobacter pylori Isolates Reveals Frequent Heteroresistance.PMID 29925646Read ↗

High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR.Semantic proximity Read ↗

Clinical Evaluation of a Real-Time PCR Assay for Simultaneous Detection of Helicobacter pylori and Genotypic Markers of Clarithromycin Resistance Directly from StoolSemantic proximity Read ↗

Molecular Detection of Antibiotic-Resistant Helicobacter pylori.Semantic proximity Read ↗

Quantitative Detection and Genotyping of Helicobacter pylori from Stool using Droplet Digital PCR Reveals Variation in Bacterial Loads that Correlates with cagA Virulence Gene CarriageSemantic proximity Read ↗

Comparative analysis of the detection of antibiotic genotypic resistance with gastric mucosa, gastric fluid, and fecal samples in patients with Helicobacter pylori infection.Semantic proximity Read ↗

Whole Genome Sequencing for Studying Helicobacter pylori Antimicrobial ResistanceSemantic proximity Read ↗

Low-Abundance and Fragmentary Helicobacter pylori DNA Detected in Phenotypically Negative Gastric Biopsies Using Targeted Sequencing.Semantic proximity Read ↗

Analysis of Helicobacter pylori genotypes in clinical gastric wash samples.Semantic proximity Read ↗

Change in Diagnosis of Helicobacter pylori Infection in the Treatment-Failure EraSemantic proximity Read ↗

Advances in Helicobacter pylori Antimicrobial Resistance Detection: From Culture‐Based to Multi‐Omics‐Based TechnologiesSemantic proximity Read ↗

Multiplex fluorescent PCR-based detection of Helicobacter pylori nucleic acid and antibiotic resistance genes in clinical stool samples: a performance evaluation from Gansu Province, China.Semantic proximity Read ↗

A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High RateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.