Article
Glioblastoma-activated pericytes support tumor growth via immunosuppression.
Cancer medicine - 1 Apr 2018
Sena Isadora F G, Paiva Ana E, Prazeres Pedro H D M, Azevedo Patrick O, Lousado Luiza, Bhutia Sujit K, Salmina Alla B, Mintz Akiva, Birbrair Alexander
Abstract excerpt
Glioblastoma multiforme is the most common and aggressive primary brain tumor, with an extremely poor prognosis. The lack of detailed knowledge about the cellular and molecular mechanisms involved in glioblastoma development restricts the design of efficient therapies. A recent study using state-of-art technologies explores the role of pericytes in the glioblastoma microenvironment. Glioblastoma-activated...
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