Article
Molecular characterization of variant D antigen expression among 56,445 blood donors in East India.
Blood transfusion = Trasfusione del sangue - 1 Jan 2025
Datta Suvro Sankha, Srivastava Kshitij, Rophina Mercy, Scaria Vinod, Liew Yew-Wah, Morrison Jenny, Millard Glenda Maree, Flegel Willy Albert
Abstract excerpt
BACKGROUND: Transfusion of red cells from RhD-positive donors to recipients lacking all or some epitopes of the D antigen can lead to the development of anti-D, potentially resulting in hemolytic transfusion reactions. Over 500 RHD alleles affect the qualitative or quantitative expression of the D antigen. There are huge differences in their prevalence among populations. Despite the distinct genetic diversity...
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