Article
Human cytomegalovirus UL144 is associated with viremia and infant development sequelae in congenital infection.
Journal of clinical microbiology - 1 Nov 2010
Waters Allison, Hassan Jaythoon, De Gascun Cillian, Kissoon Ghia, Knowles Susan, Molloy Eleanor, Connell Jeff, Hall William W
Abstract excerpt
Human cytomegalovirus (HCMV) strains may be genotyped based on polymorphisms that exist within the UL144 gene, which is one of 19 viral genes lost in attenuated laboratory strains. In the present study, UL144 genotypes in congenitally infected babies (congenital cytomegalovirus [cCMV]) were determined, and the relationship between the genotype, viral load, cytokine profile, and patient developmental outcome was...
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