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Article

Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma

6 Aug 2020

Abstract excerpt

Abstract Introduction: DICER1 is a member of RNase III family that has a pivotal role in the biogenesis of microRNAs, being important for normal development. Dysregulation of DICER1 has been described in different human tumours; however, there is insufficient data on the risk of thyroid cancer in the presence of germline DICER1 variants, particularly when focusing on the background of papillary thyroid carcinoma...

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PMID: 33718253
DOI: 10.1159/000509183

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