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Article

P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis.

Scientific reports - 22 Feb 2018

Wang Ning, Agrawal Ankita, Jørgensen Niklas Rye, Gartland Alison

Abstract excerpt

Post-menopausal osteoporosis is a condition that affects millions worldwide and places a huge socio-economic burden on society. Previous research has shown an association of loss of function SNPs in the gene for the purinergic receptor P2X7R with low bone mineral density, increased rates of bone loss and vertebral fractures in post-menopausal women. In this study we use a mouse model of oestrogen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Purinergic P2X7

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Identifiers

PMID: 29472582
DOI: 10.1038/s41598-018-21574-9
PMCID: PMC5823935

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