Article
Genes affecting progression of bacteriophage P22 infection in Salmonella identified by transposon and single gene deletion screens.
Molecular microbiology - 1 May 2018
Bohm Kaitlynne, Porwollik Steffen, Chu Weiping, Dover John A, Gilcrease Eddie B, Casjens Sherwood R, McClelland Michael, Parent Kristin N
Abstract excerpt
Bacteriophages rely on their hosts for replication, and many host genes critically determine either viral progeny production or host success via phage resistance. A random insertion transposon library of 240,000 mutants in Salmonella enterica serovar Typhimurium was used to monitor effects of individual bacterial gene disruptions on bacteriophage P22 lytic infection. These experiments revealed candidate host...
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