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Article

Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease.

Journal of pediatric gastroenterology and nutrition - 1 May 2018

Rausch John C, Lavine Joel E, Chalasani Naga, Guo Xiuqing, Kwon Soonil, Schwimmer Jeffrey B, Molleston Jean P, Loomba Rohit, Brunt Elizabeth M, Chen Yii-Der Ida, Goodarzi Mark O, Taylor Kent D, Yates Katherine P, Rotter Jerome I

Abstract excerpt

BACKGROUND AND OBJECTIVES: Nonalcoholic fatty liver disease (NAFLD) disproportionately affects Hispanic boys. Further, obesity and insulin resistance are major risk factors for NAFLD. No gene localization studies had been performed on children with biopsy-proven NAFLD. This study aims to identify genomic variants associated with increased adiposity and insulin resistance in a population of children with varying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29470286
DOI: 10.1097/MPG.0000000000001926
PMCID: PMC5916321

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