Article
Genetic Risk for Hepatic Fat among an Ethnically Diverse Cohort of Youth: The Exploring Perinatal Outcomes among Children Study.
The Journal of pediatrics - 1 May 2020
Stanislawski Maggie A, Shaw Jessica, Litkowski Elizabeth, Lange Ethan M, Perng Wei, Dabelea Dana, Lange Leslie A
Abstract excerpt
OBJECTIVE: To assess the importance of genetic and nongenetic risk factors contributing to hepatic fat accumulation in a multiethnic population of youth. STUDY DESIGN: We investigated the relationship between genetic factors and hepatic fat fraction (HFF) in 347 children aged 12.5-19.5 years. We examined 5 single nucleotide polymorphisms previously associated with HFF and a weighted genetic risk score (GRS) and...
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