Natural Extracts Abolished Lipid Accumulation in Cells Harbouring non-favourable PNPLA3 genotype.

doi:10.5604/01.3001.0010.8642

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Article

Natural Extracts Abolished Lipid Accumulation in Cells Harbouring non-favourable PNPLA3 genotype.

Annals of hepatology - 1 Mar 2018

Rojas Ángela, Gallego Paloma, Gil-Gómez Antonio, Muñoz-Hernández Rocío, Rojas Lourdes, Maldonado Rosario, Gallego Rocío, García-Valdecasas Marta, Del Campo José A, Bautista Juan D, Romero-Gómez Manuel

Abstract excerpt

Background & aims. G-allele of PNPLA3 (rs738409) favours triglycerides accumulation and steatosis. In this study, we examined the effect of quercetin and natural extracts from mushroom and artichoke on reducing lipid accumulation in hepatic cells. MATERIAL AND METHODS: Huh7.5 cells were exposed to oleic acid (OA) and treated with quercetin and extracts to observe the lipid accumulation, the intracellular-TG...

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Identifiers

PMID: 29469041
DOI: 10.5604/01.3001.0010.8642

Genes

PNPLA3
ACAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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