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Article

DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human

3 Jun 2014

Abstract excerpt

OBJECTIVE: Obesity is associated with low-grade inflammation and the infiltration of immune cells in insulin-sensitive tissues, leading to metabolic impairment. Epigenetic mechanisms control immune cell lineage determination, function and migration and are implicated in obesity and type 2 diabetes (T2D). The aim of this study was to determine the global DNA methylation profile of immune cells in obese and T2D...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Diabetes and associated disorders
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24996265
DOI: 10.1016/j.metabol.2014.05.014

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