Article
Analysis of SNPs of MC4R, GNB3 and FTO gene polymorphism in obese Saudi subjects.
African health sciences - 1 Dec 2017
Moselhy Said Salama, Alhetari Yasmeen A, Iyer Archana, Huwait Etimad A, Al-Ghamdi Maryam A, Al-Ghamdi Shareefa, Balamash Khadijah Saeed, Basuni Ashraf A, Alama Mohamed N, Kumosani Taha A, Yaghmoor Soonham Sami
Abstract excerpt
BACKGROUND: The goal of this study was to analyze the association between the FTO rs17817449 (G>T), G protein beta3 subunit (GNB3) C825T and Melanocortin 4 receptor (MC4R) A822G single nucleotide polymorphism (SNP) with obesity in Saudi subjects. METHODS: The subjects were divided into 2 groups according to BMI: Obese (BMI> 29.9) and non- obese control (BMI<24.9). Genotyping of the target genes were determined by...
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