Article
Evaluation of microribonucleic acids as potential biomarkers in the bicuspid aortic valve-associated aortopathy.
Interactive cardiovascular and thoracic surgery - 1 Jul 2018
Girdauskas Evaldas, Petersen Johannes, Neumann Niklas, Groß Tatiana, Naito Shiho, Hillebrand Mathias, Reichenspurner Hermann, Blankenberg Stefan, Zeller Tanja
Abstract excerpt
OBJECTIVES: We aimed to evaluate the impact of microRNAs to predict the bicuspid aortic valve (BAV)-associated aortopathy. METHODS: Sixty-three BAV patients (mean age 47 ± 11 years, 92% men) with root dilatation, who underwent aortic valve ± proximal aortic surgery (mean post-AVR follow-up 10.3 ± 6.9 years) were included. The BAV aortopathy entities were categorized in the 'less dilated' (aortic root <50 mm) and...
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