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Article

Association of substance dependence phenotypes in the COGA sample.

Addiction biology - 1 May 2015

Wetherill Leah, Agrawal Arpana, Kapoor Manav, Bertelsen Sarah, Bierut Laura J, Brooks Andrew, Dick Danielle, Hesselbrock Michie, Hesselbrock Victor, Koller Daniel L, Le Nhung, Nurnberger John I, Salvatore Jessica E, Schuckit Marc, Tischfield Jay A, Wang Jen-Chyong, Xuei Xiaoling, Edenberg Howard J, Porjesz Bernice, Bucholz Kathleen, Goate Alison M, Foroud Tatiana

Abstract excerpt

Alcohol and drug use disorders are individually heritable (50%). Twin studies indicate that alcohol and substance use disorders share common genetic influences, and therefore may represent a more heritable form of addiction and thus be more powerful for genetic studies. This study utilized data from 2322 subjects from 118 European-American families in the Collaborative Study on the Genetics of Alcoholism sample...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24832863
DOI: 10.1111/adb.12153
PMCID: PMC4233207

Genes

ARHGAP28

Provenance

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