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Article

A cell death assay for assessing the mitochondrial targeting of proteins.

The Journal of nutritional biochemistry - 1 Jun 2018

Camara Teixeira Daniel, Cordonier Elizabeth L, Wijeratne Subhashinee S K, Huebbe Patricia, Jamin Augusta, Jarecke Sarah, Wiebe Matthew, Zempleni Janos

Abstract excerpt

The mitochondrial proteome comprises 1000 to 1500 proteins, in addition to proteins for which the mitochondrial localization is uncertain. About 800 diseases have been linked with mutations in mitochondrial proteins. We devised a cell survival assay for assessing the mitochondrial localization in a high-throughput format. This protocol allows us to assess the mitochondrial localization of proteins and their...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29454998
DOI: 10.1016/j.jnutbio.2018.01.006
PMCID: PMC5971163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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