Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ess2 bridges transcriptional regulators and spliceosomal complexes via distinct interacting domains.

Biochemical and biophysical research communications - 4 Mar 2018

Takada Ichiro, Tsuchiya Megumi, Yanaka Kaori, Hidano Shinya, Takahashi Sayuri, Kobayashi Takashi, Ogawa Hidesato, Nakagawa Sinichi, Makishima Makoto

Abstract excerpt

Transcription and pre-mRNA splicing are complex, coupled processes that involve transcriptional co-regulators. Ess2 (also termed Dgcr14) is a nuclear protein that enhances the transcriptional activity of retinoic acid receptor-related orphan receptor gamma/gamma-t (Rorγ/γt). Ess2 is also a component of the spliceosomal C complex (containing U2, U5 and U6 snRNAs). However, the domains in Ess2 that function in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Knockdown Techniques
Share to HEK293 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nuclear Receptor Subfamily 1, Group F, Member 3

Share to Protein Interaction Domains and Motifs

Share to RNA, Small Nuclear

Share to RNA Splicing

Share to Spliceosomes

Share to Transcriptional Activation

Source

Identifiers

PMID: 29454968
DOI: 10.1016/j.bbrc.2018.02.110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ess2 bridges transcriptional regulators and spliceosomal complexes via distinct interacting domains.PMID 29454968Read ↗

The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway.Semantic proximity Read ↗

Interaction of the Epstein-Barr Virus mRNA Export Factor EB2 with Human Spen Proteins SHARP, OTT1, and a Novel Member of the Family, OTT3, Links Spen Proteins with Splicing Regulation and mRNA ExportSemantic proximity Read ↗

Cellular differentiation state modulates the mRNA export activity of SR proteins.Semantic proximity Read ↗

Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine TractsSemantic proximity Read ↗

Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins.Semantic proximity Read ↗

SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain.Semantic proximity Read ↗

Conserved regions of the Drosophila erect wing protein contribute both positively and negatively to transcriptional activity.Semantic proximity Read ↗

Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1).Semantic proximity Read ↗

Sumoylation of SUVR2 contributes to its role in transcriptional gene silencing.Semantic proximity Read ↗

hnRNP E1 and E2 have distinct roles in modulating HIV-1 gene expressionSemantic proximity Read ↗

Transcription regulation by the noncoding RNA SRG1 requires Spt2-dependent chromatin deposition in the wake of RNA polymerase II.Semantic proximity Read ↗

ELL2, a new member of an ELL family of RNA polymerase II elongation factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.